The University of North Carolina at Chapel Hill;The Johns Hopkins University
发明人:
Lai Samuel,Wang Ying-Ying,Kannan Arthi,Nunn Kennetta,Subramani Durai Babu,Cone Richard
申请号：
US201314438511
公开号：
US10100102(B2)
申请日:
2013.10.29
申请国别(地区):
美国
年份:
2018
代理人:
Myers Bigel, P.A.
摘要：
The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception in a subject using compositions and antibodies capable of trapping pathogens or sperm in mucus, thereby inhibiting transport of pathogens or sperm across mucus secretions. The subject matter further relates to methods for monitoring the effectiveness of vaccines by detecting antibodies capable of trapping pathogens in mucus.
