Bror Morein,Karin Lövgren Bengtsson,Jill Ekström,Katarina Ranlund,Kefei Hu
申请号：
US14714664
公开号：
US20150320858A1
申请日:
2015.05.18
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Fraction A of Quil A can be used together with at least one other adjuvant for the preparation of an adjuvant composition, where the included adjuvant components act synergistically to enhance level of immune response and have synergistic immunomodulating activity on the co-administered antigens or immunogens. Other adjuvants can comprise saponins, naturally occurring, synthetic or semisynthetic saponin molecules； e.g. saponins and saponin fractions from Quil A, cell wall skeleton, block polymers, TDM, lipopeptides, LPS and LPS-derivatives, Lipid A from different bacterial species and derivatives thereof, e.g., monophosphoryl lipid A, CpG variants, CT and LT or fractions thereof.
