The present invention relates to a two-component sealant comprising a first part and a second part whereina) the first part (X) comprises: (i) a polyalkyleneoxide polymer having one or more unsaturated end groups(ii) an addition reaction catalystb) the second part (Y) comprises: (i) an organosiloxane comprising one or more Si—H groups.The present invention also relates to medical devices used in connection with the sealant, mixing devices for delivering and mixing the first part and the second part of the sealant, and methods for applying the sealant.