The present invention provides an essential oil moxibustion box which at least comprises: the housing 1 which is a hollow cone-shaped body, wherein the periphery of the body is provided with more than one through hole 13 and is extending to the bottom portion for enlargedly forming the bottom seat 12, the upper portion and the lower portion are respectively formed with an opening, and the upper opening rim 11 is formed at the upper opening; the metal mesh sleeve 4 whose length is shorter than that of the housing, upper portion is provided with an opening, other portion is a mesh structure, cross-section is a U-shaped bearing body, and upper portion is provided with the flange 42 so as to make the flange 42 retained at the circumference of the upper opening rim 11of the housing 1 when it is inset at the upper opening rim 11 of the housing 1; the replaceable essential oil seat 2 upwards inserted from the lower opening of the bottom seat 12 of the housing 1 so as to perform a replacement, wherein the supporting seat 21 at the middle portion of the replaceable essential oil seat 2 is a flame retardant material and is used to be coated with or place essential oil, so that when the heat of the moxibustion is used to heat the essential oil film on the supporting seat 2 to smoke the user's skin, even the operator makes a mistake of allowing the heat of the moxibustion to reach the burning point, there is no need to worry that user's skin under the supporting seat 21 will get burned; and the heat insulation cover 6 whose upper portion and lower portion are open, wherein, when the temperature of the housing is too high during moxibustion operation, the heat insulation cover will cover the housing 1 from top to bottom, so as to prevent user's skin from getting burned. Thereby, the present invention can overcome the problem of essential oil absorption in current technique and solve the problem of rising or lowering the temperature of moxibustion.本發明此一精油艾灸盒,至少包括:一殼體1,為一內部中空的椎形胴體