CARINA ENGSTRAND ANNIKA FORSS GUNNAR GLAD BOLENNART JOHANSSON HANS OLLE JOEL JOHANSSON,JEAN LUC MALOISEL
申请号：
IN2647/DELNP/2007
公开号：
IN270715B
申请日:
2007.04.10
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to a chromatography ligand defined by the following formula (I) Ri-R2-N(R3)-R4-R5 wherein R, is a substituted or non-substituted phenyl group； R2 is a hydrocarbon chain comprising 0-4 carbon atoms； R3 is a hydrocarbon chain comprising I -3 carbon atoms； R4 is a hydrocarbon chain comprising 1-5 carbon atoms； and R5 is OH or II. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.
