Chia Tai Tianqing Pharmaceutical Group Co.,Ltd;Centaurus BioPharma Co., Ltd.
发明人:
申请号:
EP15830563.1
公开号:
EP3178821A4
申请日:
2015.08.05
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Provided are 6-aryl amino pyridone formamide compound crystal and a preparation method therefor. In the present invention, 6-(2-chlorine-4-iodopheny amino)-N-(2-hydroxyl ethyoxyl)-5-methyl-4-oxo-4,5-dihydrofuran[3,2-c]pyridine-7-formamide is dissolved in a polar aprotic solvent, a second solvent is added for recrystallization, and a crystal is obtained. The crystallization method is simple to operate and conducive for industrial production. The produced crystal has high purity, good stability, and is conductive for pharmaceutical production and storage.