Zhiwei Jiang,Aijin Wang,Hongwei Hu,Jiali Xu,Yuesong Hu,Xian Li,Yan Ye,Jie Wang,Qinglong Li
申请号:
US14002986
公开号:
US09150530B2
申请日:
2011.03.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention discloses esters of 4,9-dihydroxy-naphtho[2,3-b]furans and methods of making and using the same. The present invention also discloses conversion of the esters into therapeutically active 4,9-dihydroxy-naphtho[2,3-b]furans in vivo. The present invention furthermore discloses pharmaceutical compositions comprising the esters of 4,9-dihydroxy-naphtho[2,3-b]furans for the treatment of various indications including proliferative diseases.