According to some embodiments, system and methods are provided comprising determining one or more image locations at which motion occurred within an image volume of an object containing movable anatomical features prior to segmenting the movable anatomical features estimating motion at each of the one or more image locations correcting one or more motion artifacts in the image volume at each of the one or more image locations, where motion was estimated resulting in the generation of a final motion compensated image and segmenting one or more features of interest in the final motion compensated image. Numerous other aspects are provided.