Julia Moffitt;Bruce H. KenKnight;Sophia Wang;Imad Libbus
发明人:
Julia Moffitt,Sophia Wang,Bruce H. KenKnight,Imad Libbus
申请号：
US12543654
公开号：
US08131362B2
申请日:
2009.08.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods and devices for delivering cardiac therapy to a patient are provided. Various implantable device embodiments comprise a plurality of leads and a controller. The leads include at least one lead to be positioned within a lead path to deliver ventricular pacing pulses and to deliver neural stimulation at a site proximate to the heart to inhibit sympathetic nerve activity. The controller controls delivery of the ventricular pacing pulses in accordance with a programmed pacing mode and controls delivery of the neural stimulation. The controller is programmed to deliver remodeling control therapy (RCT) by delivering ventricular pacing to pre-excite a ventricular myocardium region to mechanically unload that region during systole, and further is programmed to deliver anti-remodeling therapy (ART) by delivering neural stimulation to inhibit sympathetic nerve activity in conjunction with RCT. Other embodiments are provided herein.
