The present invention is the preparation of naproxen, and the release profiles having, which provide, to be equivalent to the pain relief immediately for taking 440 mg (or 2 220 mg) naproxen sodium and also extend pain relief up to 24 hours.Specifically, the present invention is single solid dosage, a combination thereof unique proportions release immediately naproxen sodium product and delay to discharge naproxen sodium layer.More specifically, the present invention is single bilayer tablet, releases immediately 300 320 mg naproxen sodiums, then gradually discharges 450 480 mg naproxen sodiums.When being given as single bilayer tablet, which is capable of providing pain relief in 24 hours.Single bilayer tablet offer releases immediately (IR) naproxen sodium from one layer for initial pain relief, then continuously discharges remaining naproxen sodium from another layer to maintain to extend pain relief up to 24 hours.