LIPID NANOCAPSULE LOADED WITH CORTICOSTEROIDS FOR IMPROVING BIOAVAILABILITY AND EFFICACY IN TREATMENT OF CRONHS DISEASE

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专利权人:

发明人:

MR GAJANAN SHINDE,MS BHAVANA KULKARNI,DR ABHAY DHARAMASI

申请号：

IN201621007288

公开号：

IN201621007288A

申请日:

2016.03.02

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The basic aim of invention concerns develop lipidic nanocapsules for effective treatments of Crohns disease with the enhance bioavailability of corticosteroids. Mean particle size of develop formulation was found size less than 120 nm and Entrapment efficiency of nanocapsules more than 75%. Nanocapsules core consist of oil, lipid and drug. Nanocapsules improve the oral bioavailability and first pass metabolism of drug. Said lipid nanocapsules prepared by phase inversion method and modified solvent evaporation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/