Andrea Carfi,Antu Dey,Aemro Kassa,Indresh K. Srivastava
申请号：
US14408466
公开号：
US20150183835A1
申请日:
2013.06.17
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides an isolated polypeptide comprising an HIV gp120 polypeptide or soluble gp140 polypeptide stabilized in a conformation which exposes both CD4-bound and CD4-binding site epitopes. The invention also provides immunogenic compositions and methods of treating and preventing infection with HIV.
