Monoclonal Antibodies are added to human Tau Tau, compositions comprising such Antibodies, and Methods of use of such Antibodies against Tau for the treatment of Neurodegenerative Diseases including Alzheimer's disease, Progressive Supranuclear Palsy and P Ick.Anticuerpos monoclonales que se agregan a tau humana, composiciones que comprenden tales anticuerpos tau, y métodos de uso de tales anticuerpos contra tau para el tratamiento de enfermedades neurodegenerativas incluyendo enfermedad de Alzheimer, Parálisis Supranuclear Progresiva y enfermedad de Pick.