CHEN, AUSTIN CHIH-YU,DUBE, DANIEL,FOURNIER, PIERRE-ANDRE,GRIMM, ERICH L.,LACOMBE, PATRICK,LALIBERTE, SEBASTIEN,MACDONALD, DWIGHT,MACKAY, D. BRUCE,MCKAY, DANIEL JAMES,WU, TOM YAO-HSIANG
申请号：
EP09749373
公开号：
EP2300453A4
申请日:
2009.05.21
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position Isoqumolone and having the Formula (I): The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
