Refers to a Pharmaceutical composition comprising: (a) ombrabulin was administered at a dose of 15 to 35 mg \/ m2 b) as a Derivative of Taxane paclitaxel was given at a dose of 175 mg \/ m2 or or docetaxel was administered at a dose of 60 or 75mg \/ m2 (c) Platinum Derivative of Ta L as cisplatin was administered at a dose of 75mg \/ m2 or carboplatin was administered to twoAUC is 5 or 6. This combination is well tolerated, antitumor, exacerbate the toxicity of each of the antitumor agents and is useful in the treatment of Advanced Solid tumors by Stabilizing or inducing a partial or complete tumour regressionSE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) OMBRABULINA QUE SE ADMINISTRA A UNA DOSIS DE 15 A 35MG/M2 B) UN DERIVADO DE TAXANO TAL COMO PACLITAXEL QUE SE ADMINISTRA A UNA DOSIS DE 175 O 200MG/M2 O DOCETAXEL QUE SE ADMINISTRA A UNA DOSIS DE 60 O 75MG/M2 C) UN DERIVADO DE PLATINO TAL COMO CISPLATINO QUE SE ADMINISTRA A UNA DOSIS DE 75MG/M2 O CARBOPLATINO QUE SE ADMINISTRA A UNA DOSIS DE 5 O 6 AUC. DICHA COMBINACION ANTITUMORAL SE TOLERA BIEN, NO EXACERBA LA TOXICIDAD DE CADA UNO DE LOS AGENTES ANTITUMORALES Y ES UTIL EN EL TRATAMIENTO DE TUMORES SOLIDOS AVANZADOS ESTABILIZANDO O INDUCIENDO UNA REGRESION PARCIAL O COMPLETA DEL TUMOR
