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Solid oral dosage form containing an enhancer
专利权人:
Thomas W. I. Leonard
发明人:
Thomas W. I. Leonard
申请号:
US12481952
公开号:
US08883201B2
申请日:
2009.06.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
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