Solid oral dosage form containing an enhancer

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专利权人:

Thomas W. I. Leonard

发明人:

Thomas W. I. Leonard

申请号：

US12481952

公开号：

US08883201B2

申请日:

2009.06.10

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.

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