Rapidly disintegrating oral Preparation comprising Granules comprising a Drug, a disintegrating Agent, a Binder, a masking Agent and a solubilizing agent； Preparation method； its use for the prophylaxis and / or treatment of bipolar illness.
The present invention provides a preparation with improved disintegration property, a preparation showing improved bioavailability of a medicament, production methods thereof and the like. A rapidly disintegrating preparation comprising granules comprising a medicament coated with a coating layer containing sugar or sugar alcohol； and a disintegrant. A production method of a rapidly disintegrating preparation including a step of producing granules comprising a medicament, a step of forming a coating layer containing sugar or sugar alcohol on the obtained granules and a step of mixing the coated granules with a disintegrant and molding the mixture.<；p>；Preparació；n farmacé；utica de desintegració；n rá；pida que comprende grá；nulos que comprenden (S)-N-[2-(1,6,7,8-tetrahidro-2H-indeno [5,4-b] furan-8-il)etil] propionamida recubiertos con una capa de recubrimiento que contiene azú；car o alcohol de azú；car； y un agente de desintegració；n, donde el azú；car o alcohol de azú；car se selecciona del grupo que consiste de lactosa, fructosa, glucosa, manitol, sorbitol, eritritol, y sucrosa； el agente de desintegració；n se selecciona desde el grupo que consiste de aminoá；cidos, almidó；n, almidó；n de maí；z, carmelosa, carmelosa de sodio, carmelosa de calcio, croscarmelosa de sodio, crospovidona, hidroxipropilcelulosa de baja sustitució；n, hidroxipropil almidó；n , y carboximetil almidó；n só；dico. Metodo para fabricar a la preparació；n farmacé；utica de desintegració；n rá；pida.<；/p>；
