Presented herein are methods for treatment of diseases or conditions related to fibrosis. Compounds, or pharmaceutically acceptable salts thereof or pharmaceutical compositions thereof provide for the treatment of diseases or conditions related to fibrosis. The methods utilize the compounds kynurenine, kynurenic acid and xanthurenic acid, and various analogues, related structures and pharmaceutical compositions thereof, wherein the compounds are represented by one or more compounds represented by Formulas I, II, or II as set out below: