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In vitro and in vivo anti-inflammatory effects of a sesquiterpene lactone extract from chicory (Cichorium intybus L.)
专利权人:
Rutgers; The State University of New Jersey
发明人:
Ilic, Nebojsa,Schmidt, Barbara,Raskin, Ilya,Ripoll, Christophe
申请号:
AU2006309191
公开号:
AU2006309191B2
申请日:
2006.10.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
A method of preparing a chicory extract enriched with sesquiterpene lactones is provided. The method includes performing an initial extraction chicory in a polar solvent, such as methanol or ethanol, at ambient temperature to form an alcoholic extract. The alcoholic extract is subsequently defatted with a non-polar solvent, preferably hexane or n-heptane. A second extraction of the defatted alcoholic extract is performed with a solvent which is more polar than the solvent used in the defatting process and less polar than the solvent used in the initial extraction, for example, it can be chosen from the group consisting of ethyl acetate, n-butanol, isopropanol, n-propanol, dichloromethane, acetonitrile, and mixtures thereof resulting in a sesquiterpene lactones enriched extract, preferably containing at least 60 % sesquiterpene lactones.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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