Cyclic phosphonate substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Stephane Bogen,Vinay Girijavallabhan,Quang Truong,Ping Chen,Frank Bennett,Angela Kerekes,Qun Dang,David B. Olsen,Ian Davies

申请号：

US14899008

公开号：

US09765107B2

申请日:

2014.06.16

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to Cyclic Phosphonate Substituted Nucleoside Derivatives of Formula (I): (structure) and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein, as well as to compositions and methods of using the Cyclic Phosphonate Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/