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Microfluidic System for Reproducing Functional Units of Tissues and Organs In Vitro
专利权人:
INC.;NORTIS
发明人:
Thomas Neumann,Anna A. Tourovskaia,Mark E. Fauver,Greg Kramer,Elizabeth McClure,Henning Mann
申请号:
US16025806
公开号:
US20190062684A1
申请日:
2018.07.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A microfluidic system including a number of microfluidic devices having a first perfusion path and a second separate perfusion path; the microfluidic devices each also having a chamber containing a matrix, where the matrix surrounds at least one void whose lumen is in fluidic connection exclusively with the first perfusion path, where the at least one void is populated with at least one cell type in such way that the cells are in direct contact with the matrix; where the matrix is in fluidic connection exclusively with the second separate perfusion path. The microfluidic devices are integrated onto a platform; and each of the microfluidic devices mimics at least a partial organ module.
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