PROBLEM TO BE SOLVED: To provide an infectious Plasmodium sporozoite grown in vitro. SOLUTION: The target is an in vitro-reared Plasmodium sporozoite in a human host region in which sporozoites from the reproductive mother cell stage to the sporozoite stage are outside the mosquito, and a method for producing the sporozoite. In vitro-reared infectious Plasmodium sporozoites (SPZ) in the human host region, with sporozoites from the reproductive maternal stage to the sporozoite stage outside to mosquitoes, especially P. parasites. Plasmodium falcipalum, P. vivax, P.M. ovale, P.M. malarlae and P.M. knowisi and how to produce it. [Selection diagram] None【課題】ｉｎ ｖｉｔｒｏで成長させた感染性Ｐｌａｓｍｏｄｉｕｍスポロゾイトの提供。【解決手段】生殖母細胞期からスポロゾイト期までのスポロゴニーが蚊に対して外側にある、ヒト宿主域のｉｎ ｖｉｔｒｏ飼育されたＰｌａｓｍｏｄｉｕｍスポロゾイトと、これを産生する方法を対象とする。生殖母細胞期からスポロゾイト期までのスポロゴニーが蚊に対して外側にある、ヒト宿主域のｉｎ ｖｉｔｒｏ飼育された感染性Ｐｌａｓｍｏｄｉｕｍスポロゾイト（ＳＰＺ）、特に、Ｐ．ｆａｌｃｉｐａｒｕｍ、Ｐ．ｖｉｖａｘ、Ｐ．ｏｖａｌｅ、Ｐ．ｍａｌａｒｌａｅおよびＰ．ｋｎｏｗｌｅｓｉと、これを産生する方法。【選択図】なし
