BRACKETT, JOHN M.,JONAITIS, DAVID T.,LAI, WEI,LIU, JIH HUA,PARENT, STEPHAN D.,SHEN, JINYU
申请号:
CA2674347
公开号:
CA2674347C
申请日:
2007.12.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to crystalline forms of racemic ilaprazole,2[[(4-methoxy-3-methyl-2-pyridinyl)-methyl]sulfinyl]-5-(1H-pyrrol-1-yl) 1H-Benzimidazole. The invention also relatesto a pharmaceutical composition for inhibiting gastric acid secretioncomprising a crystallineForm of ilaprazole according to the invention in an amount effective toinhibit gastric acidsecretion and a pharmaceutically acceptable carrier. The invention alsoprovides methods oftreatment for various acid-related gastrointestinal (GI) disorders. Ilaprazolehas the followingstructural Formula (I):(see formula I)