PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE CHILDREN'S MEDICAL CENTER CORPORATION
发明人:
Joshua R. SANES,Xin DUAN,Mu QIAO,Zhigang HE,Fengfeng BEI,Yuanyuan LIU
申请号:
US16639232
公开号:
US20200237868A1
申请日:
2018.08.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are methods for promoting neuronal outgrowth in a subject with a neuronal lesion in their CNS by administering effective amounts of a pro-regenerative OPN fragment, optionally with IGF1 and/or BDNF. A voltage gated potassium channel blocker can also be administered. Pharmaceutical compositions, devices for administration, and kits are also disclosed.