Disclosed is an isolated antibody that binds Cadherin-17 (CDH 17), comprising: (a) a heavy chain comprising an amino acid sequence with at least 85% sequence identity to SEQ ID NO: 27 and (b) a light chain comprising an amino acid sequence with at least 85% sequence identity to SEQ ID NO: 31 wherein the sequences are as defined in the specification. Also disclosed is the use of the antibody for treating cancer.