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LH-TYPE BISPECIFIC ANTIBODY
专利权人:
发明人:
申请号:
EP10755725.8
公开号:
EP2412808A1
申请日:
2010.01.04
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
[Problem]Provided are a novel diabody type bispecific antibody, the function of which as a bispecific antibody is improved to provide a higher additional value, such as cost saving caused by a reduction in dose, to a drug and a method for producing the same.[Solution]A humanized diabody type bispecific antibody (LH-diabody type bispecific antibody) characterized in that an L-chain is located in the N-terminal side in each polypeptide (LH type) a humanized high-functional bispecific antibody which contains said LH diabody type bispecific antibody a nucleic acid molecule encoding both of two kinds of single-stranded polypeptides constituting said bispecific antibody and a method for producing said antibody which comprises culturing a host cell having been transformed by an expression vector containing said nucleic acid molecule.
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中国工程科技知识中心
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