PROBLEM TO BE SOLVED: To provide a practical method for producing lamellarin &alpha-20 sulfate or its analog, having high flexibility.SOLUTION: This method for obtaining a compound (I) is provided by reacting a compound (II) with a compound (III) to obtain a compound (IV), then reacting with a compound (V) to obtain a compound (VI), and obtaining the lamellarin compound (XI) through the selective deprotection of P3, hydrolysis, decaboxylation, oxidative ring closure and oxidation, and then through the selective deprotection of P2, sulfuric acid esterification, the selective deprotection of P1 and the deprotection of P4 to obtain the compound (I).COPYRIGHT: (C)2007,JPO&INPIT【課題】ラメラリンα-20サルフェートまたはその類縁体の柔軟性が高く、実用的な製造方法を提供すること。【解決手段】化合物(II)と化合物(III)を反応させて化合物(IV)を得、次いで化合物(V)と反応させて化合物(VI)を得、次いでP3の選択的脱保護、加水分解、脱炭酸、酸化閉環および酸化を経てラメラリン化合物(XI)を得、次いでP2の選択的脱保護、硫酸エステル化、P1の選択的脱保護およびP4の脱保護を経て化合物(I)を得る。(式中の記号は明細書に定義したとおりである。)【選択図】 なし
