James A. Gregory;Michael J. Hannon;Carla S. Jones;Stephen P. Mayfield
发明人:
Stephen P. Mayfield,James A. Gregory,Carla S. Jones,Michael J. Hannon
申请号:
US14123519
公开号:
US09422347B2
申请日:
2012.05.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to the production of malaria transmission blocking vaccines in single-celled green algae, particularly algae of the genus Chlamydomonas, e.g., Chlamydomonas reinhardtii; the immunogenic Plasmodium polypeptides produced and compositions comprising them; and methods for preventing, ameliorating, reducing, delaying, treating and blocking the transmission of malaria by administration of immunogenic Plasmodium polypeptides produced in an algal host cell.