Bruno Botta,Alberto Gulino,Maurizio Botta,Mattia Mori,Lucia Di Marcotullio,Paola Infante,Francesca Ghirga,Sara Toscano,Cinzia Ingallina,Romina Alfonsi
申请号:
US14898955
公开号:
US10093642B2
申请日:
2014.06.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention concerns compounds that selectively inhibit the activity of the Hedgehog (Hh) pathway, their preparation and uses thereof. The compounds of the present invention are useful in treating Hh-dependent tumors, such as medulloblastoma (MB).