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PROMÉDICAMENT HYDROSOLUBLE ACTIVÉ CHIMIQUEMENT
专利权人:
Ltd.;Sumitomo Dainippon Pharma Co.
发明人:
申请号:
EP18859459.2
公开号:
EP3686182A1
申请日:
2018.09.21
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention addresses the problem of providing a novel chemically activated water-soluble prodrug. The present invention provides a compound represented by formula (1), or a pharmacologically acceptable salt thereof (in the formula, A represents A-0; X1 and X2 are the same as or different from each other and each independently represent a hydroxyl group or -O-C(=O)-Y-(C(R1A)(R1B))n-NH-R2, where X1 and X2 are not simultaneously hydroxyl groups, n is 2, 3, or 4, Y represents an oxygen atom or -NR4, R1A and R1B are the same as or different from each other and each independently represent a hydrogen atom, etc., and R2 represents a hydrogen atom, etc.; and Ra to Rd are optionally present, are the same as or different from each other, and each independently represent a hydrogen atom, etc.).
来源网站:
中国工程科技知识中心
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