This Hair is bright to provide Gong Jing Body of bent Ma Duo With former times cloth Class. This Hair is bright to be related to C16H25NO2 He Gong Jing Body of eutectic Xing Cheng Body of the Election from NSAID/ former times cloth Class, the Should of Yu System Prepare its method and its Men as Drug object or in Drug Wu System Elixirs of Yonging are used, and Geng Te Do is that the Should controlled in Treatment pain with what is used. The Real of Gifted Election is applied in mode, and Gong Jing Body is (racemization)-C16H25NO2 HCl- plug Come former times cloth (1:1).本發明提供了曲馬多與昔布類的共晶體。本發明涉及曲馬多和選自NSAID/昔布類的共晶形成體的共晶體、用於製備其的方法以及它們作爲藥物或在藥物製劑中的應用,更特別是用於治療疼痛中的應用。在優選的實施方式中,共晶體是(消旋)‑曲馬多•HCl‑塞來昔布(1:1)。