LOW DENSITY LIPOPROTEIN RECEPTOR-MEDIATED siRNA DELIVERY

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专利权人:

发明人:

Jon E. Chatterton

申请号：

US15352754

公开号：

US20170056507A1

申请日:

2016.11.16

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention provides interfering RNA molecule-ligand conjugates useful as a delivery system for delivering interfering RNA molecules to a cell in vitro or in vivo. The conjugates comprise a ligand that can bind to a low density lipoprotein receptor (LDLR) or LDLR family member. Therapeutic uses for the conjugates are also provided.

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