The Benzochromene derivatives of what Formulas I are closed in system of the present invention,The wherein meaning that there is various parameters what to indicate herein, it and is to close the liquid crystal media that includes the grade compounds, it and is to close the what grade media in electrical-optical display, purposes especially in TN, OCB, LCOS and/or IPS-LCD, and be the purposes for closing the what grade compounds and its physiologically acceptable derivative as therapeutic activity composition.本發明係關於式I之苯并色烯衍生物,其中各種參數具有於本文中指示之含義,且係關於包含該等化合物之液晶介質,且係關於該等介質在電-光顯示器中,尤其在TN、OCB、LCOS及/或IPS-LCD中之用途,且係關於該等化合物及其生理學上可接受之衍生物作為治療活性成份之用途。