FASTING MIMICKING DIET (FMD) AND GLUCOSE LOWERING DRUGS PROTECT NORMAL CELLS AND GENERATE CANCER SENSITIZING CONDITIONS IN RESPONSE TO STANDARD AND HIGH GLUCOSE CONDITIONS INDUCED BY RAPAMYCIN AND DEXAMETHASONE
A method for treating a hyperglycemia and hyperglycemia-dependent side effects in a subject undergoing chemotherapy includes a step of identifying a subject undergoing chemotherapy and being administered a hyperglycemia-inducing agent. Short-term starvation or a fasting mimicking diet is administered for a first time period to the subject to prevent hyperglycemia and sensitization to chemotherapy associated with increased glucose levels. The STS-mimicking drug Metformin is administrated between STS/FMD cycles to maintain STS-/FMD-like conditions during the re-feeding period.
