As for long-cherished desire, as the converse operation glaze for the GABA receptor which possesses, the 5 sub unit because it is used as the medicine which remedies the recognitive function fault of the down symptom patient it regards the chemical compound which has functional selectivity. In addition, long-cherished desire as the converse operation glaze for the GABA receptor which possesses, the 5 sub unit in order to prepare the medicine which remedies the recognitive function fault of the down symptom patient regards the usage of the chemical compound which has functional selectivity. Furthermore, it regards the pharmacy constituent in order long-cherished desire includes, as the converse operation glaze for the GABA receptor which possesses 5 sub unit the chemical compound which has functional selectivity, or, the appropriateness the salt, the porietokishiru conversion castor oil and the dimethyl sulfoxide which can be allowed pharmacy (DMSO) to remedy the recognitive function fault of the down symptom patient. In addition, as for long-cherished desire, the recognitive function in the down symptom patient as the converse operation glaze for the GABA receptor which includes 5 sub unit one which has functional selectivity or by prescribing the pharmacy effective tonnage which, the patient of the chemical compound above that needs to the patient, is reinforced, or, heavily seriously it remedies or to ease manner in order recognitive function fault, or has been shown. Furthermore, long-cherished desire storage power fault, of the down symptom patient like regards the remedy manner of the recognitive function fault ability to learn fault or that both fault.本願は、ダウン症患者の認識機能障害を治療する薬剤として用いられるための、α5サブユニットを有するGABAA受容体に対する逆作用薬としての機能的選択性を備える化合物に関する。また、本願は、ダウン症患者の認識機能障害を治療する薬剤を調製するための、α5サブユニットを有するGABAA受容体に対する逆作用薬としての機能的選択性を備える化合物の使用方法に関する。さらに、本願は、α5サブユニットを有するGABAA受容体に対する逆作用薬としての機能的選択性を備える化合物、又は、その適切な薬学的に許容できる塩、ポリエトキシル化ひまし油及びジメチルスルホキシド(DMSO)を含む、ダウン症患者の認識機能障害を治療するための薬学的組成
