An embodiment of a method for assessing cardiovascular disease in a user with a body region using a mobile computing device including a camera module, includes receiving a time series of image data of a body region of the user, the time series of image data captured during a time period； generating a photoplethysmogram dataset from the time series of image data； generating a processed PPG dataset； determining a cardiovascular parameter value of the user based on the processed PPG dataset； fitting a chronobiological model to (1) the cardiovascular parameter value, and (2) a subsequent cardiovascular parameter value, characterizing a cardiovascular parameter variation over time of the user based on the fitted chronobiological model； and presenting an analysis of the cardiovascular parameter variation to the user at the mobile computing device.
