According to embodiments, there is provided a medical apparatus including one or more sterile pre-filled syringe, one or more first protective container including the one or more sterile pre-filled syringe, wherein the first protective container may be completely or partially filled with an inert or non-inert gas, wherein the one or more first protective container is impermeable to moisture and/or sterilizing agents, and a second protective container including one or more medical components and the one or more first protective container, wherein the second protective container may be, but is not necessarily, completely or partially filled with an inert or non-inert gas. In some aspects, a package mostly impermeable to bacteria including the first and second protective containers is also completely or partially filled with an inert or non-inert gas.
