ANTI-C-MET ANTIBODY AND ANTI-C-MET ANTIBODY-CYTOTOXIC DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF

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专利权人:

Suzhou Suncadia Biopharmaceuticals Co., Ltd.;Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.

发明人:

Jiajian LIU,Lianshan ZHANG,Weikang TAO,Yayuan FU,Ling ZHANG,Dong MA,Dongbing CUI,Yali WANG,Jianyan XU,Jindong LIANG,Ying ZHANG,Guiyang JIANG,Junzhuan QIU,Ziyong SUN,Jiping ZHA,Jingping WEI

申请号：

US15565928

公开号：

US20180110875A1

申请日:

2016.04.07

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Provided are an anti-c-Met antibody or an antigen binding fragment thereof, and an anti-c-Met antibody-cytotoxic drug conjugate, wherein the antibody or antigen binding fragment thereof is a chimeric antibody or a humanized antibody. Also provided are pharmaceutical compositions containing the humanized anti-c-Met antibody or antigen binding fragment thereof, the antibody-cytotoxic drug conjugate, or pharmaceutically acceptable salts or solvents thereof, that are used in the treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/