Esa Kuusela,Emmi Ruokokoski,Santtu Ollila,Janne Nord,Jarkko Peltola
申请号:
US15890051
公开号:
US10512791B2
申请日:
2018.02.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A cost function is constructed so as to guide an optimization process to achieve similar coverage for all targets simultaneously in a concurrent radiation treatment of multiple targets, so that a single scaling factor may be used in a plan normalization to achieve the desired coverage for all the targets. The cost function includes a component that favors a solution that attains similar target coverages for all targets, as well as a component that favors a solution that approaches the desired target coverage value for each individual target. The cost function includes a max term relating to deficiencies of actual target coverages with respect to a desired target coverage, or alternatively a soft-max term relating to deviations of actual target coverages with respect to an average target coverage, as well as to deficiencies of actual target coverages with respect to a desired target coverage.