WILLIAM L. BETTS III,LEE ALANI SELVEY,MARLON V. CARLOS,PAUL MAFFUID,YUN SHAN,RYAN M. HART,ZEZHI JESSE SHAO,DEAM WINDATE GIVEN III
申请号:
PT09752512
公开号:
PT2364142T
申请日:
2009.10.27
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
The present invention relates to certain compositions of a 5-HT2A serotonin receptor modulator and methods for their preparation. The compositions disclosed herein are useful for increasing slow wave sleep, improving sleep consolidation, improving sleep maintenance and improving sleep quality, and for treating insomnia and related sleep disorders, dyssomnias, parasomnias and nonrestorative sleep and the like. The compositions disclosed herein are further useful for treating platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, thrombosis, asthma or symptoms thereof, agitation or symptoms thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorders, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, diabetic-related disorders and progressive multifocal leukoencephalopathy and the like.