MOGRABI, JOSEF; JOSEF;MOGRABI;HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT
发明人:
ILAN, YARON
申请号：
EP13793975
公开号：
EP2854798A4
申请日:
2013.05.23
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Pharmaceutical compositions including combinations of protective agents selected from isosilybin B, methylsulfonylmethane (MSM), phosphatidylcholine, cysteine (Cys), seleno-cysteine (Se-Cys), ribose-cysteine (RibCys), N-acetylcysteine (NAC), N-acetylcysteine-amide (AD4), methionine (Met) and S-adenosylmethionine (SAM) for reducing and/or preventing drug-induced toxicity, such as acetaminophen-induced toxicity. The compositions may be formulated with or without acetaminophen, and accordingly may be used as safe formulations of acetaminophen with reduced risk of causing liver damage, or as an antidote for the treatment of acetaminophen overdose. Methods for treating acetaminophen intoxication.
