DERIVES ANTHRAPYRIDAZONES A SUBSTITUTION ASYMETRIQUE UTILISES COMME CYTOSTATIQUES

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专利权人:

BS-154 SP. Z O.O.

发明人:

BOROWSKI, EDWARD,STEFANSKA, BARBARA,DZIEDUSZYCKA, MARIA,CYBULSKI, MARCIN,SZELEJEWSKI, WIESLAW,OBUKOWICZ, JANUSZ,BONTEMPS-GRACZ, MARIA,WYSOCKA, MALGORZATA,MAZERSKI, JAN,PUNDA, PAWEL,WIETRZYK, JOANNA

申请号：

CA2831388

公开号：

CA2831388A1

申请日:

2012.04.13

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The invention relates to the new, asymmetrically substituted derivatives of 2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione and their use as cytostatics exhibiting activity against tumor cells, especially against cells with multidrug resistance (MDR). In particular, the invention concerns derivatives of 2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione represented by the general formula (I).

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