A cylindrical holder for housing a pharmaceutical product container in a hand-piece of a surgical instrument for perforating dense tissue of a human or animal body and injecting a pharmaceutical product behind or in the tissue. The cylindrical holder connects an injection needle with the container. The holder has a tubular wall for receiving the container. The tubular wall includes contact areas defined by bridges of material subsisting between cut-outs located along circumferential rows, the bridges of material having deflections towards the inside of the cylindrical holder. A surgical instrument for perforating dense tissue of a human or animal body and injecting a pharmaceutical product behind or in the tissue, and includes a hand-piece and the cylindrical holder.
