PROBLEM TO BE SOLVED: To provide an endoscope apparatus which uses an imaging unit with two imaging elements laminatingly mounted thereon to enable simultaneous observation of reflection from a subject caused by white light and fluorescence from the subject caused by excitation light with a desired performance attained.SOLUTION: Used is an imaging unit 21 on which are mounted laminatingly, from the side receiving light from a subject, a first light permissive film 60 shielding excitation light, a first imaging element 83 photoelectrically converting white light, and a second imaging element 87 photoelectrically converting fluorescence which has transmitted through the first light permissive film 60 and the first imaging element 83, such that the reflection from the subject and the fluorescence from the subject caused by the excitation light are observed simultaneously. A timing control unit 69 causes an excitation light source K2 to illuminate at least during an illuminating period of a white light source K1 to allow that an image signal from the second imaging element 87 is read simultaneously with the reading of an imaging signal from the first imaging element 83 during at least a part of a period during which the image signal from the first imaging element 83 is read.SELECTED DRAWING: Figure 8【課題】２つの撮像素子が積層配置された撮像部を用いた白色光による被検体からの反射光と励起光による同被検体からの蛍光の同時観察を所望の性能を満たして実行可能な内視鏡装置を提供すること。【解決手段】被検体からの光の入射側から順に、励起光を遮断する第１光透過膜６０、白色光を光電変換する第１撮像素子８３、第１光透過膜６０及び第１撮像素子８３を透過した蛍光を光電変換する第２撮像素子８７が積層配置された撮像部２１を用いて、被検体からの反射光と励起光による同被検体からの蛍光の同時観察を行う。タイミング制御部６９は、励起光用光源Ｋ２を、少なくとも白色光用光源Ｋ１の発光期間には発光させ、第２撮像素子８７からの画像信号の読み出しを、第１撮像素子８３からの画像信号の読み出し期間の少なくとも一部の読み出し期間に、第１撮像素子８３からの画像信号の読み出しと同時に行う。【選択図】図８
