NOUVEAUX EPITOPES DE CELLULES ET NOUVELLE COMBINAISON D'EPITOPES DE CELLULES DESTINES A ETRE UTILISES DANS L'IMMUNOTHERAPIE DU MYELOME ET D'AUTRES CANCERS
RAMMENSEE, HANS-GEORG,STICKEL, JULIANE,KOWALEWSKI, DANIEL,STEVANOVIC, STEFAN,WALZ, SIMON
申请号:
CA2990507
公开号:
CA2990507A1
申请日:
2016.06.21
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular myeloma. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.