Irinotecan hydrochloride composite phospholipid composition, preparation method and use thereof

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专利权人:

Shanghai Jingfeng Pharmaceutical Co., Ltd.;Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Chinese Academy of Sciences;Shanghai Institute of Materia Medica

发明人:

Li, Yaping,Chen, Lingli,Zheng, Zhaolei,Zhang, Zhiwen,Gu, Wangwen

申请号：

AU2015230539

公开号：

AU2015230539B2

申请日:

2015.03.06

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

An irinotecan hydrochloride composite phospholipid composition, preparation method and uses thereof in the preparation of drugs for treating tumors or drug resistant tumors. The composite phospholipid composition comprises irinotecan hydrochloride, composite phospholipid, cholesterol, long-circulating membrane material, surfactant and a buffer medium. The composition improves stability of lipid formulation and the anti-tumor effect of irinotecan hydrochloride, and can overcome multidrug resistance of a tumor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/