SCHWEDE WOLFGANG,MOLLER CARSTEN,KLAR ULRICH,ROTGERI ANDREA,BONE WILHELM
申请号:
NZ62341710
公开号:
NZ623417A
申请日:
2010.07.07
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
The disclosure relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of formula (I) and their stereoisomers, salts, solvate or solvate of the salts, including all crystal modifications wherein the variables are as defined in the specification.. These compounds exhibit progesterone-antagonistic effects and are useful in the treatment and/or prophylaxis of fibroids of the uterus, endometriosis, heavy menstrual bleeds, meningiomas, hormone-dependent breast cancers and complaints associated with the menopause or for fertility control and emergency contraception.