GEORGES BERTRAND VICTOR GILBERT,BROWN CARLTON BRADLEY
申请号:
IN6148/DELNP/2015
公开号:
IN2015DN06148A
申请日:
2015.07.13
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
A pharmaceutical composition comprising at least two peptides of from 15 to 60 amino acids in length selected from peptides comprising a sequence of at least 15 contiguous amino acids of one of the sequences shown in SEQ ID NOs: 1 to 4 or of a sequence having at least 80% identity to one of the sequences shown in SEQ ID NOs: to 4 wherein each peptide comprises at least one CD8+ T cell epitope and/or at least one CD4+ T cell epitope and wherein each peptide elicits a response in peripheral blood mononuclear cells (PBMC) from at least one chronically infected HBV individual in an 10 in vitroassay.