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heterocyclic carboxylic acids as soluble guanylate cyclase activators
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
CHRISTOPHER RONALD SARKO,JEHROD BURNETT BRENNEMAN,JOHN DAVID GINN,JOHN WESTBROOK,MAOLIN YU,MICHAEL D. LOWE,TAMARA DENISE HOPKINS,ZHONGHUA ZHANG
申请号:
BR112017000943
公开号:
BR112017000943A2
申请日:
2015.07.21
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention relates to the compounds of formula I: ie pharmaceutically acceptable salts thereof, wherein r1, r2, r3, r5, r6, r7, r8, r9, b, v, w, x, y, zem are as follows: defined herein. The invention likewise relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in such processes.a presente invenção refere-se aos compostos de fórmula i: i e sais farmaceuticamente aceitáveis dos mesmos, em que r1 , r2, r3, r5, r6, r7, r8, r9, b, v, w, x, y, z e m são como aqui definidos. a invenção da mesma forma refere-se às composições farmacêuticas compreendendo estes compostos, métodos de uso destes compostos no tratamento de várias doenças e transtornos, processos para preparar estes compostos e intermediários úteis nestes processos.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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