ASSOCIATION INSTITUT DE MYOLOGIES;INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MEDICALE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6);UNIVERSITÄT BERN
发明人:
CHRISTIAN LEUMANN,LUIS GARCIA,THOMAS VOIT
申请号:
BR112014009066
公开号:
BR112014009066A2
申请日:
2012.10.12
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention relates to a nucleic acid molecule containing a sequence of tricyclo nucleosides joined by internucleoside phosphorothioate linkage. The invention also relates to synthetic antisense oligonucleotides and to methods employing the same.